Product Description
Th2 Modulator
What Is It?
Th2 Modulator contains a blend of N-acetyl-L-cysteine (NAC), quercetin, perilla seed and astragalus extracts to help modulate the Th2 immune response, to support TH1/Th2 balance, self-tissue response, and mucosal health.
Features
• Part of the PureResponse™ Immune Protocol for healthy immune balance and function
• Offers support for self-tissue response, particularly for the sinus, respiratory and gastrointestinal systems
• Contains perilla seed extract for a concentrated source of polyphenols, rosmarinic acid, luteolin and other beneficial compounds to support healthy modulation of mucosal immune responses to environmental factors
Modulate Th2 Immune Response:
Th2 Modulator helps support healthy modulation of Th2 cytokines, and eosinophil and mast cell activity. Th2 response is affected by stress, aging, and cytokine changes resulting from metabolic, hormonal, physiological, and environmental factors. Perilla maintains healthy upper respiratory cytokine levels in animal models of Th2 dominance. Quercetin is known for its antioxidant activity and immune support properties, including support for Th1/Th2 balance and cytokine balance. Preliminary research indicates that astragalus supports a healthy Th1/Th2 balance through modulation of Th2-associated cytokines‡
Mucosal Health: Th2 Modulator helps maintain healthy modulation of mucosal immune responses to environmental factors. Th2 modulation may be indicated when addressing immune balance in the sinus, respiratory, urinary, and intestinal tracts. Perilla supports cytokine homeostasis of G.I. mucosal tissue. N-acetyl-L-cysteine (NAC) offers mucolytic properties and promotes tissue levels of glutathione, a key component of the antioxidant defense system, to support the body’s natural defense system. Lymphocytes rely on glutathione to function properly. It is believed to be through this antioxidant mechanism that NAC supports healthy Th1/Th2 balance and cytokine production to maintain tissue health. A multicenter, randomized, double-blind trial with 262 participants indicated that NAC supplementation for six months supported upper respiratory tract and immune system health.
What is the Source?
N-Acetyl-L-Cysteine is derived from corn dextrose fermentation. Quercetin is derived from Fava d’anta tree (Dimorphandra mollis) pods and cat’s claw (Uncaria tormentosa) leaves. Perilla extract is derived from Perilla frutescens L. seed. Astragalus extract is derived from Astragalus membranaceus root.
Recommendations:
Pure Encapsulations® recommends 2 capsules, 1–2 times daily, with meals, or as directed by a health professional.
Are There Any Potential Side Effects or Precautions?
If pregnant or lactating, consult your physician before taking this product. Rare side effects of NAC can include nausea, vomiting, headache, dry mouth, dizziness, or abdominal pain. Consult your physician for more information. Are There Any Potential Drug Interactions? Quercetin may react with calcium channel blockers, estradiol, and immune suppressive drugs. NAC may interact with nitroglycerin and metoclopramide. Consult your physician for more information.

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