Product Description

Th1 Support

What Is It?

Th1 Support offers a blend of berberine, baicalin from Chinese skullcap, sulforaphane from broccoli, ginger, and zinc to promote healthy Th1-predominant cellular immune response and innate immunity.

Features

• Part of the PureResponse™ Immune Protocol for healthy immune balance and function

• Maintains healthy immune biomarkers and cytokine balance related to cell tissue health and comfort

Enhancement of Immune Defense: Th1 Support is designed to support healthy activation of Th1 cells to promote innate immunity and cellmediated immune defenses. Th1 responses are affected by stress, aging, and cytokine changes resulting from metabolic, hormonal, physiological, and environmental factors. The product helps balance cytokine production in order to promote Th1 differentiation. Clinical and preclinical studies show that berberine positively influences immune biomarkers related to cell and tissue health. In vitro evidence suggests that berberine supports maturation of T cells into Th1 cells and production of IL-12, an important Th1- promoting cytokine. Sulforaphane from broccoli promotes various aspects of immunological homeostasis that maintain the health of mucosal cells. Cellular and animal models also suggest support for Th1-promoting interferon gamma (IFN2) and IL-2 production. Baicalin from skullcap offers support for healthy production of IFN2, promoting Th1-type immune responses, according to animal studies. Ginger modulates the production of IL-6 and TNF-alpha, according to preclinical data.

What is the Source?

Zinc is sourced from elemental ore. Picolinate is synthetic. Berberine HCl is derived from Phellodendron amurense bark and Sargent’s barberry (Berberis sargentiana). Chinese skullcap extract is derived from Scutellaria baicalensis root. Broccoli sprout concentrate is derived from Brassica oleracea italic whole sprouts. Ginger extract is derived from Zingiber officinale root. Hypoallergenic plant fiber is derived from pine cellulose.

Recommendations

Pure Encapsulations® recommends 2 capsules, 1–2 times daily, with meals, or as directed by a health professional.

Are There Any Potential Side Effects or Precautions?

Not to be taken by pregnant or lactating women. Berberine has had reports of headache, nausea, vomiting, abdominal bloating, hypotension and slowed heart rate in the literature. There have been reports of G.I. upset from skullcap and zinc. There are reports of sedation, cognitive impairment, and vivid dreams from skullcap. Consult your physician for more information.

Are There Any Potential Drug Interactions?

Individuals on blood pressure or anti-diabetes medications and taking berberine may require blood pressure or blood glucose monitoring. Ginger and broccoli sprout extract may be contraindicated with blood thinning medications. Skullcap may be contraindicated with CNS depressant or sedative medication due to an additive effect. Consult your physician for more information.

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